Human CTCF Recombinant Protein (N-His) (HW366022)

Name: Human CTCF Recombinant Protein (N-His)
Brand: abinScience
SKU: HW366022
Price: 211 USD
Availability: InStock

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1mg

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Каталожный номер	HW366022
Описание	Recombinant Human CTCF Protein, N-His (HW366022) expressed in E. coli, spanning Thr265-Arg572. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	P49711, Q61164, Q9R1D1
Длина белка	Thr265-Arg572
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	38.93 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	11-zinc finger protein, CCCTC-binding factor, CTCF, CTCFL paralog, Transcriptional repressor CTCF
Фон	Transcriptional repressor CTCF is a ~82 kDa protein. Chromatin binding factor that binds to DNA sequence specific sites and regulates the 3D structure of chromatin. Binds together strands of DNA, thus forming chromatin loops, and anchors DNA to cellular structures, such as the nuclear lamina. Defines the boundaries between active and heterochromatic DNA via binding to chromatin insulators, thereby preventing interaction between promoter and nearby enhancers and silencers. Participates in the allele-specific gene expression at the imprinted IGF2/H19 gene locus. On the maternal allele, binding within the H19 imprinting control region (ICR) mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to IGF2. 1. Ishihara, K. et al. (2006) Molecular cell 23, 733-42. PMID: 16949368 2. Majumder, P. et al. (2008) The Journal of experimental medicine 205, 785-98. PMID: 18347100 3. Fu, Y. et al. (2008) PLoS genetics 4, e1000138. PMID: 18654629 4. Mishiro, T. et al. (2009) The EMBO journal 28, 1234-45. PMID: 19322193
Примечание	For research use only

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Human CTCF Recombinant Protein (N-His).pdf

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