Human CYP2B6 Recombinant Protein (N-His) (HD015012)

Name: Human CYP2B6 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD015012
Price: 211 USD
Availability: InStock

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Número de catálogo	HD015012
Descripción	Recombinant Human CYP2B6 Protein, N-His (HD015012) expressed in E. coli, spanning Gly41-Arg491. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	P20813
Longitud de proteína	Gly41-Arg491
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	54.11 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	1,4-cineole 2-exo-monooxygenase, CYP2B6, CYPIIB6, Cytochrome P450 2B6, Cytochrome P450 IIB1, EC:1.14.13.-
Fondo	Cytochrome P450 2B6 is a ~56 kDa protein. A cytochrome P450 monooxygenase involved in the metabolism of endocannabinoids and steroids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the epoxidation of double bonds of arachidonoylethanolamide (anandamide) to 8,9-, 11,12-, and 14,15-epoxyeicosatrienoic acid ethanolamides (EpETrE-EAs), potentially modulating endocannabinoid system signaling. Hydroxylates steroid hormones, including testosterone at C-16 and estrogens at C-2. Plays a role in the oxidative metabolism of xenobiotics, including plant lipids and drugs. 1. Lee, AJ. et al. (2003) Endocrinology 144, 3382-98. PMID: 12865317 2. Sridar, C. et al. (2011) Drug metabolism and disposition: the biological fate of chemicals 39, 782-8. PMID: 21289075 3. Miyazawa, M. et al. (2001) Xenobiotica; the fate of foreign compounds in biological systems 31, 713-23. PMID: 11695850 4. Shah, MB. et al. (2012) Biochemistry 51, 7225-38. PMID: 22909231
Nota	For research use only

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Datasheet

Human CYP2B6 Recombinant Protein (N-His).pdf

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