Human CYP2J2 Recombinant Protein (N-His) (HD745012)

Name: Human CYP2J2 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD745012
Price: 211 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HD745012
Description	Recombinant Human CYP2J2 Protein, N-His (HD745012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	P51589
Longueur de protéine	Gly54-Val502
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	Albendazole monooxygenase (hydroxylating), Albendazole monooxygenase (sulfoxide-forming), Arachidonic acid epoxygenase, CYP2J2, CYPIIJ2, Cytochrome P450 2J2, EC:1.14.14.-, EC:1.14.14.73, EC:1.14.14.74, EC:5.4.4.7, Hydroperoxy icosatetraenoate isomerase
Contexte	Cytochrome P450 2J2 is a ~57 kDa protein. A cytochrome P450 monooxygenase involved in the metabolism of polyunsaturated fatty acids (PUFA) in the cardiovascular system. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the epoxidation of double bonds of PUFA. Converts arachidonic acid to four regioisomeric epoxyeicosatrienoic acids (EpETrE), likely playing a major role in the epoxidation of endogenous cardiac arachidonic acid pools. In endothelial cells, participates in eicosanoids metabolism by converting hydroperoxide species into hydroxy epoxy metabolites. 1. Lucas, D. et al. (2010) Journal of lipid research 51, 1125-33. PMID: 19965576 2. Wu, S. et al. (1996) The Journal of biological chemistry 271, 3460-8. PMID: 8631948 3. Chawengsub, Y. et al. (2009) The Journal of biological chemistry 284, 31280-90. PMID: 19737933 4. Lee, CA. et al. (2010) Drug metabolism and disposition: the biological fate of chemicals 38, 347-56. PMID: 19923256 5. Wu, Z. et al. (2013) Antimicrobial agents and chemotherapy 57, 5448-56. PMID: 23959307
Note	For research use only

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Human CYP2J2 Recombinant Protein (N-His).pdf

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