Human CYP4F8 Recombinant Protein (N-His) (HD835012)

Name: Human CYP4F8 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD835012
Price: 211 USD
Availability: InStock

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概要

カタログ番号	HD835012
説明	Recombinant Human CYP4F8 Protein, N-His (HD835012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
発現システム	E. coli
アクセッション番号	P98187
タンパク質長	Thr38-Gly520
アプリケーション	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種	Homo sapiens (Human)
性質	Recombinant
エンドトキシンレベル	Please contact with the lab for this information.
純度	>90% as determined by SDS-PAGE.
形態	Lyophilized
保存バッファー	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
再構成	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	CYP4F8, CYPIVF8, Cytochrome P450 4F8, EC:1.14.14.1
背景	Cytochrome P450 4F8 is a ~59 kDa protein. A cytochrome P450 monooxygenase involved in the metabolism of endogenous polyunsaturated fatty acids (PUFAs) and their oxygenated derivatives (oxylipins). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon hydrogen bonds, with preference for omega-1 and omega-2 positions. Hydroxylates (5Z,8Z,11Z,14Z)-eicosatetraenoic acid (arachidonate) predominantly at omega-2 position to form (18R)-hydroxyeicosatetraenoic acid (18R-HETE). Exhibits omega-1 hydroxylase activity toward prostaglandin (PG) H1, PGH2 and PGI2. 1. Bylund, J. et al. (2000) The Journal of biological chemistry 275, 21844-9. PMID: 10791960 2. Stark, K. et al. (2005) Prostaglandins & other lipid mediators 75, 47-64. PMID: 15789615 3. Stark, K. et al. (2005) Archives of biochemistry and biophysics 441, 174-81. PMID: 16112640
注意事項	For research use only

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参考文献

データシート

Human CYP4F8 Recombinant Protein (N-His).pdf

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Formula

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C₁ (Stock Conc.)

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Human CYP4F8 Recombinant Protein (N-His) (HD835012)

概要

イメージ

参考文献

データシート

SDS

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