Human DAB2IP Recombinant Protein (N-His) (HV442012)

Name: Human DAB2IP Recombinant Protein (N-His)
Brand: abinScience
SKU: HV442012
Price: 211 USD
Availability: InStock

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Número de catálogo	HV442012
Descripción	Recombinant Human DAB2IP Protein, N-His (HV442012) expressed in E. coli, spanning Glu154-Thr655. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	Q5VWQ8
Longitud de proteína	Glu154-Thr655
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	59.59 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	AF9Q34, AIP-1, AIP1, ASK-interacting protein 1, DAB2 interaction protein, DAB2-interacting protein, DAB2IP, DOC-2/DAB-2 interactive protein, Disabled homolog 2-interacting protein, KIAA1743
Fondo	Disabled homolog 2-interacting protein is a ~131 kDa protein. Functions as a scaffold protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Involved in several processes such as innate immune response, inflammation and cell growth inhibition, apoptosis, cell survival, angiogenesis, cell migration and maturation. Also plays a role in cell cycle checkpoint control; reduces G1 phase cyclin levels resulting in G0/G1 cell cycle arrest. Mediates signal transduction by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF), interferon (IFN) or lipopolysaccharide (LPS). Modulates the balance between phosphatidylinositol 3-kinase (PI3K)-AKT-mediated cell survival and apoptosis stimulated kinase (MAP3K5)-JNK signaling pathways; sequesters both AKT1 and MAP3K5 and counterbalances the activity of each kinase by modulating their phosphorylation status in response to pro-inflammatory stimuli. 1. Luo, X. et al. (2017) Oncotarget 8, 85415-85427. PMID: 29156729
Nota	For research use only

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Datasheet

Human DAB2IP Recombinant Protein (N-His).pdf

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