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| カタログ番号 | HC205011 |
|---|---|
| 説明 |
Recombinant Human DDX17 Protein, C-Strep (HC205011) expressed in Insect Cells, spanning Gly111-Gly556. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | Insect cells |
| アクセッション番号 | Q92841 |
| タンパク質長 | Gly111-Gly556 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 52.39 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | DDX17, DEAD box protein 17, DEAD box protein p72, DEAD box protein p82, EC:3.6.4.13, Probable ATP-dependent RNA helicase DDX17, RNA-dependent helicase p72 |
| 背景 | Probable ATP-dependent RNA helicase DDX17 is a ~80 kDa protein. As an RNA helicase, unwinds RNA and alters RNA structures through ATP binding and hydrolysis. Involved in multiple cellular processes, including pre-mRNA splicing, alternative splicing, ribosomal RNA processing and miRNA processing, as well as transcription regulation. Regulates the alternative splicing of exons exhibiting specific features. For instance, promotes the inclusion of AC-rich alternative exons in CD44 transcripts. This function requires the RNA helicase activity. 1. Hönig, A. et al. (2002) Molecular and cellular biology 22, 5698-707. PMID: 12138182 2. Germann, S. et al. (2012) Oncogene 31, 4536-49. PMID: 22266867 3. Dardenne, E. et al. (2012) Nature structural & molecular biology 19, 1139-46. PMID: 23022728 4. Dardenne, E. et al. (2014) Cell reports 7, 1900-13. PMID: 24910439 |
| 注意事項 | For research use only |
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