Human DDX39A Recombinant Protein (N-His) (HD747012)

Name: Human DDX39A Recombinant Protein (N-His)
Brand: abinScience
SKU: HD747012
Price: 211 USD
Availability: InStock

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100ug
1mg

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Каталожный номер	HD747012
Описание	Recombinant Human DDX39A Protein, N-His (HD747012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	O00148
Длина белка	Arg47-Arg427
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	ATP-dependent RNA helicase DDX39A, DDX39, DDX39A, DEAD box protein 39, EC:3.6.4.13, Nuclear RNA helicase URH49
Фон	ATP-dependent RNA helicase DDX39A is a ~49 kDa protein. Helicase that plays an essential role in mRNA export and is involved in multiple steps in RNA metabolism including alternative splicing. Regulates nuclear mRNA export to the cytoplasm through association with ECD. Also involved in spliceosomal uridine-rich small nuclear RNA (U snRNA) export by stimulating the RNA binding of adapter PHAX. Plays a role in the negative regulation of type I IFN production by increasing the nuclear retention of antiviral transcripts and thus reducing their protein expression. Independently of the interferon pathway, plays an antiviral role against alphaviruses by binding to a 5' conserved sequence element in the viral genomic RNA. 1. Saleem, I. et al. (2021) Molecular and cellular biology 41, e0010321. PMID: 33941617 2. Banerjee, S. et al. (2024) Nucleic acids research 52, 8534-8551. PMID: 38801080 3. Taniguchi, I. et al. (2024) Nucleic acids research 52, 10668-10682. PMID: 39011894 4. Shi, P. et al. (2020) Journal of immunology (Baltimore, Md. : 1950) 205, 168-180. PMID: 32393512 5. Tapescu, I. et al. (2023) Molecular cell 83, 4174-4189.e7. PMID: 37949067
Примечание	For research use only

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Даташит

Human DDX39A Recombinant Protein (N-His).pdf

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Formula

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

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Working Solution

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V₂ (Working Vol.)

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