Human DROSHA Recombinant Protein (N-His) (HV966022)

Name: Human DROSHA Recombinant Protein (N-His)
Brand: abinScience
SKU: HV966022
Price: 211 USD
Availability: InStock

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概要

カタログ番号	HV966022
説明	Recombinant Human DROSHA Protein, N-His (HV966022) expressed in E. coli, spanning Leu876-Asp1233. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
発現システム	E. coli
アクセッション番号	Q9NRR4
タンパク質長	Leu876-Asp1233
アプリケーション	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種	Homo sapiens (Human)
性質	Recombinant
エンドトキシンレベル	Please contact with the lab for this information.
純度	>90% as determined by SDS-PAGE.
予測分子量	43.44 kDa
形態	Lyophilized
保存バッファー	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
再構成	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	DROSHA, EC:3.1.26.3, Protein Drosha, RN3, RNASE3L, RNASEN, RNase III, Ribonuclease 3, Ribonuclease III, p241
背景	Ribonuclease 3 is a ~159 kDa protein. Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA.
注意事項	For research use only

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参考文献

データシート

Human DROSHA Recombinant Protein (N-His).pdf

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Human DROSHA Recombinant Protein (N-His) (HV966022)

概要

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参考文献

データシート

SDS

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