Human ELP1 Recombinant Protein (N-His) (HC974012)

Name: Human ELP1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC974012
Price: 211 USD
Availability: InStock

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Número de catálogo	HC974012
Descripción	Recombinant Human ELP1 Protein, N-His (HC974012) expressed in E. coli, spanning Met1-Thr377. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	O95163
Longitud de proteína	Met1-Thr377
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	44.52 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	ELP1, Elongator complex protein 1, IKAP, IKBKAP, IKK complex-associated protein, IkappaB kinase complex-associated protein, p150
Fondo	Elongator complex protein 1 is a ~150 kDa protein. Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. Regulates the migration and branching of projection neurons in the developing cerebral cortex, through a process depending on alpha-tubulin acetylation. ELP1 binds to tRNA, mediating interaction of the elongator complex with tRNA. May act as a scaffold protein that assembles active IKK-MAP3K14 complexes (IKKA, IKKB and MAP3K14/NIK). 1. Dalwadi, U. et al. (2018) Cellular and molecular life sciences : CMLS 75, 1613-1622. PMID: 29332244 2. Cohen, L. et al. (1998) Nature 395, 292-6. PMID: 9751059
Nota	For research use only

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Datasheet

Human ELP1 Recombinant Protein (N-His).pdf

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