Human ELP1 Recombinant Protein (N-His) (HC974012)

Name: Human ELP1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC974012
Price: 211 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HC974012
Description	Recombinant Human ELP1 Protein, N-His (HC974012) expressed in E. coli, spanning Met1-Thr377. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	O95163
Longueur de protéine	Met1-Thr377
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	44.52 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	ELP1, Elongator complex protein 1, IKAP, IKBKAP, IKK complex-associated protein, IkappaB kinase complex-associated protein, p150
Contexte	Elongator complex protein 1 is a ~150 kDa protein. Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. Regulates the migration and branching of projection neurons in the developing cerebral cortex, through a process depending on alpha-tubulin acetylation. ELP1 binds to tRNA, mediating interaction of the elongator complex with tRNA. May act as a scaffold protein that assembles active IKK-MAP3K14 complexes (IKKA, IKKB and MAP3K14/NIK). 1. Dalwadi, U. et al. (2018) Cellular and molecular life sciences : CMLS 75, 1613-1622. PMID: 29332244 2. Cohen, L. et al. (1998) Nature 395, 292-6. PMID: 9751059
Note	For research use only

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Human ELP1 Recombinant Protein (N-His).pdf

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