

| Numéro de catalogue | HD784012 |
|---|---|
| Description |
Recombinant Human EOMES Protein, N-His (HD784012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | O95936 |
| Longueur de protéine | Ala267-Ser461 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | EOMES, Eomesodermin homolog, T-box brain protein 2, T-brain-2, TBR-2, TBR2 |
| Contexte | Eomesodermin homolog is a ~72 kDa protein. Functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification. Plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Required for differentiation and migration of unipolar dendritic brush cells. Also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes. 1. Baala, L. et al. (2007) Nature genetics 39, 454-6. PMID: 17353897 2. McDonough, A. et al. (2020) Frontiers in neuroscience 14, 598548. PMID: 33488348 3. Atreya, I. et al. (2007) Gut 56, 1572-8. PMID: 17566017 |
| Note | For research use only |
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