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Human FAM107A Recombinant Protein (N-His) (HD748012)

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概要
カタログ番号HD748012
説明
Recombinant Human FAM107A Protein, N-His (HD748012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% as determined by SDS-PAGE.
発現システムE. coli
アクセッション番号O95990
タンパク質長Met1-Leu144
アプリケーションELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種Homo sapiens (Human)
性質 Recombinant
エンドトキシンレベル Please contact with the lab for this information.
純度 >90% as determined by SDS-PAGE.
形態 Lyophilized
保存バッファー Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

再構成 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名Actin-associated protein FAM107A, DRR1, Down-regulated in renal cell carcinoma 1, FAM107A, Protein TU3A, TU3A
背景

Actin-associated protein FAM107A is a ~17 kDa protein. Stress-inducible actin-binding protein that plays a role in synaptic and cognitive functions by modulating actin filamentous (F-actin) dynamics. Mediates polymerization of globular actin to F-actin. Also binds to, stabilizes and bundles F-actin. Involved in synaptic function by regulating neurite outgrowth in an actin-dependent manner and for the acquisition of hippocampus-dependent cognitive function, such as learning and long-term memory. Plays a role in the actin and microtubule cytoskeleton organization; negatively regulates focal adhesion (FA) assembly promoting malignant glial cell migration in an actin-, microtubule- and MAP1A-dependent manner.

1. Le, PU. et al. (2010) Oncogene 29, 4636-47. PMID: 20543869
2. Wang, L. et al. (2000) Genes, chromosomes & cancer 27, 1-10. PMID: 10564580
3. Mu, P. et al. (2017) Oncogene 36, 5745-5756. PMID: 28604741
注意事項 For research use only
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参考文献
Formula
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