Human FFAR2 Recombinant Protein (N-GST & C-His) (HC898012)

Name: Human FFAR2 Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HC898012
Price: 211 USD
Availability: InStock

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1mg

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Каталожный номер	HC898012
Описание	Recombinant Human FFAR2 Protein, N-GST & C-His (HC898012) expressed in E. coli, spanning Ser277-Glu330. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	O15552
Длина белка	Ser277-Glu330
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	33.91 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	FFA2, FFAR2, Free fatty acid receptor 2, G-protein coupled receptor 43, GPCR43, GPR43
Фон	Free fatty acid receptor 2 is a ~37 kDa protein. G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family. Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. 1. Brown, AJ. et al. (2003) The Journal of biological chemistry 278, 11312-9. PMID: 12496283 2. Le Poul, E. et al. (2003) The Journal of biological chemistry 278, 25481-9. PMID: 12711604 3. Hudson, BD. et al. (2013) The Journal of biological chemistry 288, 17296-312. PMID: 23589301 4. Zhang, J. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 185, 6899-910. PMID: 21037097 5. Hudson, BD. et al. (2012) The Journal of biological chemistry 287, 41195-209. PMID: 23066016
Примечание	For research use only

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Human FFAR2 Recombinant Protein (N-GST & C-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

C₁ × V₁ = C₂ × V₂

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C₁ (Stock Conc.)

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V₂ (Working Vol.)

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