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| カタログ番号 | HB940022 |
|---|---|
| 説明 |
Recombinant Human FUT1 Protein, N-His (HB940022) expressed in E. coli, spanning Thr80-Pro365. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | P19526 |
| タンパク質長 | Thr80-Pro365 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 34.98 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | Alpha(1,2)FT 1, Blood group H alpha 2-fucosyltransferase, EC:2.4.1.344, EC:2.4.1.69, FUT1, Fucosyltransferase 1, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1, Galactoside alpha-(1,2)-fucosyltransferase 1, H, HSC, Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT1, Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT1 |
| 背景 | Galactoside alpha-(1,2)-fucosyltransferase 1 is a ~41 kDa protein. Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose residue of glycoconjugates through an alpha(1,2) linkage leading to H antigen synthesis that is an intermediate substrate in the synthesis of ABO blood group antigens. H antigen is essential for maturation of the glomerular layer of the main olfactory bulb, in cell migration and early cell-cell contacts during tumor associated angiogenesis. Preferentially fucosylates soluble lactose and to a lesser extent fucosylates glycolipids gangliosides GA1 and GM1a. 1. Larsen, RD. et al. (1990) Proceedings of the National Academy of Sciences of the United States of America 87, 6674-8. PMID: 2118655 2. Moehler, TM. et al. (2008) Journal of cellular physiology 215, 27-36. PMID: 18205178 |
| 注意事項 | For research use only |
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