Human GFI1 Recombinant Protein (N-His) (HD909012)

Name: Human GFI1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD909012
Price: 211 USD
Availability: InStock

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Número de catálogo	HD909012
Descripción	Recombinant Human GFI1 Protein, N-His (HD909012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	Q99684
Longitud de proteína	Lys256-Lys422
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	GFI1, Growth factor independent protein 1, ZNF163, Zinc finger protein 163, Zinc finger protein Gfi-1
Fondo	Zinc finger protein Gfi-1 is a ~45 kDa protein. Transcription repressor essential for hematopoiesis. Functions in a cell-context and development-specific manner. Binds to 5'-TAAATCAC[AT]GCA-3' in the promoter region of a large number of genes. Component of several complexes, including the EHMT2-GFI1-HDAC1, AJUBA-GFI1-HDAC1 and RCOR-GFI-KDM1A-HDAC complexes, that suppress, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development. Regulates neutrophil differentiation, promotes proliferation of lymphoid cells, and is required for granulocyte development. 1. Rödel, B. et al. (2000) The EMBO journal 19, 5845-55. PMID: 11060035 2. Dahl, R. et al. (2007) The Journal of biological chemistry 282, 6473-83. PMID: 17197705 3. Marteijn, JA. et al. (2007) Blood 110, 3128-35. PMID: 17646546 4. Montoya-Durango, DE. et al. (2008) The Journal of biological chemistry 283, 32056-65. PMID: 18805794 5. Basu, S. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 1433-8. PMID: 19164764 6. Liu, Q. et al. (2010) Oncogene 29, 2843-52. PMID: 20190815 7. Zweidler-Mckay, PA. et al. (1996) Molecular and cellular biology 16, 4024-34. PMID: 8754800 10. Sharif-Askari, E. et al. (2010) Molecular and cellular biology 30, 3929-42. PMID: 20547752
Nota	For research use only

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Human GFI1 Recombinant Protein (N-His).pdf

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