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Human GLRB Recombinant Protein (N-His) (HD052012)

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Vista general
Número de catálogoHD052012
Descripción
Recombinant Human GLRB Protein, N-His (HD052012) expressed in E. coli, spanning Ser41-Gln265. Purity: >90% by SDS-PAGE.
Highlights
  • ●His-Tagged — N-terminal 6×His tag for IMAC purification.
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresiónE. coli
Número de accesoP48167
Longitud de proteínaSer41-Gln265
AplicacionesELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
EspeciesHomo sapiens (Human)
Naturaleza Recombinant
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >90% as determined by SDS-PAGE.
Peso molecular predicho 28.40 kDa
Forma Lyophilized
Buffer de almacenamiento Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Reconstitución Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosGLRB, Glycine receptor 58 kDa subunit, Glycine receptor subunit beta
Fondo

Glycine receptor subunit beta is a ~56 kDa protein. Subunit of heteromeric glycine-gated chloride channels. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents.

1. Rees, MI. et al. (2002) Human molecular genetics 11, 853-60. PMID: 11929858
2. Miller, PS. et al. (2004) British journal of pharmacology 143, 19-26. PMID: 15302677
3. Miller, PS. et al. (2005) The Journal of biological chemistry 280, 37877-84. PMID: 16144831
4. Yang, Z. et al. (2012) Biochemistry 51, 5229-31. PMID: 22715885
5. James, VM. et al. (2013) Neurobiology of disease 52, 137-49. PMID: 23238346
6. Zhang, Y. et al. (2015) Neuropharmacology 89, 391-7. PMID: 25445488
7. Yu, H. et al. (2021) Neuron 109, 2707-2716.e6. PMID: 34473954
8. Handford, CA. et al. (1996) Brain research. Molecular brain research 35, 211-9. PMID: 8717357
Nota For research use only
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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