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| カタログ番号 | HD052012 |
|---|---|
| 説明 |
Recombinant Human GLRB Protein, N-His (HD052012) expressed in E. coli, spanning Ser41-Gln265. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | P48167 |
| タンパク質長 | Ser41-Gln265 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 28.40 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | GLRB, Glycine receptor 58 kDa subunit, Glycine receptor subunit beta |
| 背景 | Glycine receptor subunit beta is a ~56 kDa protein. Subunit of heteromeric glycine-gated chloride channels. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents. 1. Rees, MI. et al. (2002) Human molecular genetics 11, 853-60. PMID: 11929858 2. Miller, PS. et al. (2004) British journal of pharmacology 143, 19-26. PMID: 15302677 3. Miller, PS. et al. (2005) The Journal of biological chemistry 280, 37877-84. PMID: 16144831 4. Yang, Z. et al. (2012) Biochemistry 51, 5229-31. PMID: 22715885 5. James, VM. et al. (2013) Neurobiology of disease 52, 137-49. PMID: 23238346 6. Zhang, Y. et al. (2015) Neuropharmacology 89, 391-7. PMID: 25445488 7. Yu, H. et al. (2021) Neuron 109, 2707-2716.e6. PMID: 34473954 8. Handford, CA. et al. (1996) Brain research. Molecular brain research 35, 211-9. PMID: 8717357 |
| 注意事項 | For research use only |
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