

| Каталожный номер | HD970012 |
|---|---|
| Описание |
Recombinant Human GPSM2 Protein, N-His (HD970012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Система экспрессии | E. coli |
| Номер доступа | P81274 |
| Длина белка | Met1-Gly376 |
| Применения | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Виды | Homo sapiens (Human) |
| Характер | Recombinant |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | G-protein-signaling modulator 2, GPSM2, LGN, Mosaic protein LGN |
| Фон | G-protein-signaling modulator 2 is a ~76 kDa protein. Plays an important role in mitotic spindle pole organization via its interaction with NUMA1. Required for cortical dynein-dynactin complex recruitment during metaphase. Plays a role in metaphase spindle orientation. Also plays an important role in asymmetric cell divisions. Has guanine nucleotide dissociation inhibitor (GDI) activity towards G(i) alpha proteins, such as GNAI1 and GNAI3, and thereby regulates their activity. 1. Du, Q. et al. (2001) Nature cell biology 3, 1069-75. PMID: 11781568 2. Yasumi, M. et al. (2005) The Journal of biological chemistry 280, 6761-5. PMID: 15632202 3. Zhu, J. et al. (2011) Molecular cell 43, 418-31. PMID: 21816348 4. Kiyomitsu, T. et al. (2012) Nature cell biology 14, 311-7. PMID: 22327364 |
| Примечание | For research use only |
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