Human GREM1 Recombinant Protein (C-Fc) (HT246021)

Name: Human GREM1 Recombinant Protein (C-Fc)
Brand: abinScience
SKU: HT246021
Price: 298 USD
Availability: InStock

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50ug
100ug
1mg

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Каталожный номер	HT246021
Описание	Recombinant Human GREM1 Protein, C-Fc (HT246021) expressed in Mammalian Cells, spanning Met1-Asp182. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии	Mammalian cells
Номер доступа	O60565
Длина белка	Met1-Asp182
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	47.10 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	CKTSF1B1, Cell proliferation-inducing gene 2 protein, Cysteine knot superfamily 1, BMP antagonist 1, DAN domain family member 2, DAND2, DRM, Down-regulated in Mos-transformed cells protein, GREM1, Gremlin-1, IHG-2, Increased in high glucose protein 2
Фон	Gremlin-1 is a ~20 kDa protein. Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro). Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed. 1. Kišonaitė, M. et al. (2016) The Biochemical journal 473, 1593-604. PMID: 27036124
Примечание	For research use only