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Human GUCY2D Recombinant Protein (N-His) (HD844012)

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  • 1mg
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Vista general
Número de catálogoHD844012
Descripción
Recombinant Human GUCY2D Protein, N-His (HD844012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% as determined by SDS-PAGE.
Sistema de expresiónE. coli
Número de accesoQ02846
Longitud de proteínaAla52-Pro453
AplicacionesELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
EspeciesHomo sapiens (Human)
Naturaleza Recombinant
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >90% as determined by SDS-PAGE.
Forma Lyophilized
Buffer de almacenamiento Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Reconstitución Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosCG-E, CORD6, EC:4.6.1.2, GUC1A4, GUC2D, GUCY2D, Guanylate cyclase 2D, retinal, RETGC, RETGC-1, RETGC1, ROS-GC, Retinal guanylyl cyclase 1, Rod outer segment membrane guanylate cyclase
Fondo

Retinal guanylyl cyclase 1 is a ~120 kDa protein. Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-associated proteins to the photoreceptor outer segment membrane.

1. Tucker, CL. et al. (2004) Molecular vision 10, 297-303. PMID: 15123990
2. Peshenko, IV. et al. (2011) Biochemistry 50, 9511-9. PMID: 21928830
3. Peshenko, IV. et al. (2015) The Journal of biological chemistry 290, 19584-96. PMID: 26100624
4. Wimberg, H. et al. (2018) Frontiers in molecular neuroscience 11, 348. PMID: 30319355
5. Tucker, CL. et al. (1998) Proceedings of the National Academy of Sciences of the United States of America 95, 5993-7. PMID: 9600905
Nota For research use only
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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