

| Numéro de catalogue | HD844012 |
|---|---|
| Description |
Recombinant Human GUCY2D Protein, N-His (HD844012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | Q02846 |
| Longueur de protéine | Ala52-Pro453 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | CG-E, CORD6, EC:4.6.1.2, GUC1A4, GUC2D, GUCY2D, Guanylate cyclase 2D, retinal, RETGC, RETGC-1, RETGC1, ROS-GC, Retinal guanylyl cyclase 1, Rod outer segment membrane guanylate cyclase |
| Contexte | Retinal guanylyl cyclase 1 is a ~120 kDa protein. Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-associated proteins to the photoreceptor outer segment membrane. 1. Tucker, CL. et al. (2004) Molecular vision 10, 297-303. PMID: 15123990 2. Peshenko, IV. et al. (2011) Biochemistry 50, 9511-9. PMID: 21928830 3. Peshenko, IV. et al. (2015) The Journal of biological chemistry 290, 19584-96. PMID: 26100624 4. Wimberg, H. et al. (2018) Frontiers in molecular neuroscience 11, 348. PMID: 30319355 5. Tucker, CL. et al. (1998) Proceedings of the National Academy of Sciences of the United States of America 95, 5993-7. PMID: 9600905 |
| Note | For research use only |
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