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Human GUCY2D Recombinant Protein (N-His) (HD844012)

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概要
カタログ番号HD844012
説明
Recombinant Human GUCY2D Protein, N-His (HD844012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% as determined by SDS-PAGE.
発現システムE. coli
アクセッション番号Q02846
タンパク質長Ala52-Pro453
アプリケーションELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種Homo sapiens (Human)
性質 Recombinant
エンドトキシンレベル Please contact with the lab for this information.
純度 >90% as determined by SDS-PAGE.
形態 Lyophilized
保存バッファー Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

再構成 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名CG-E, CORD6, EC:4.6.1.2, GUC1A4, GUC2D, GUCY2D, Guanylate cyclase 2D, retinal, RETGC, RETGC-1, RETGC1, ROS-GC, Retinal guanylyl cyclase 1, Rod outer segment membrane guanylate cyclase
背景

Retinal guanylyl cyclase 1 is a ~120 kDa protein. Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-associated proteins to the photoreceptor outer segment membrane.

1. Tucker, CL. et al. (2004) Molecular vision 10, 297-303. PMID: 15123990
2. Peshenko, IV. et al. (2011) Biochemistry 50, 9511-9. PMID: 21928830
3. Peshenko, IV. et al. (2015) The Journal of biological chemistry 290, 19584-96. PMID: 26100624
4. Wimberg, H. et al. (2018) Frontiers in molecular neuroscience 11, 348. PMID: 30319355
5. Tucker, CL. et al. (1998) Proceedings of the National Academy of Sciences of the United States of America 95, 5993-7. PMID: 9600905
注意事項 For research use only
イメージ
参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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