

| Каталожный номер | HD844012 |
|---|---|
| Описание |
Recombinant Human GUCY2D Protein, N-His (HD844012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Система экспрессии | E. coli |
| Номер доступа | Q02846 |
| Длина белка | Ala52-Pro453 |
| Применения | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Виды | Homo sapiens (Human) |
| Характер | Recombinant |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | CG-E, CORD6, EC:4.6.1.2, GUC1A4, GUC2D, GUCY2D, Guanylate cyclase 2D, retinal, RETGC, RETGC-1, RETGC1, ROS-GC, Retinal guanylyl cyclase 1, Rod outer segment membrane guanylate cyclase |
| Фон | Retinal guanylyl cyclase 1 is a ~120 kDa protein. Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-associated proteins to the photoreceptor outer segment membrane. 1. Tucker, CL. et al. (2004) Molecular vision 10, 297-303. PMID: 15123990 2. Peshenko, IV. et al. (2011) Biochemistry 50, 9511-9. PMID: 21928830 3. Peshenko, IV. et al. (2015) The Journal of biological chemistry 290, 19584-96. PMID: 26100624 4. Wimberg, H. et al. (2018) Frontiers in molecular neuroscience 11, 348. PMID: 30319355 5. Tucker, CL. et al. (1998) Proceedings of the National Academy of Sciences of the United States of America 95, 5993-7. PMID: 9600905 |
| Примечание | For research use only |
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