

| Numéro de catalogue | HC067022 |
|---|---|
| Description |
Recombinant Human H1-0 Protein, N-His-SUMO & C-Strep (HC067022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | P07305 |
| Longueur de protéine | Lys27-Lys97 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | H1-0, H1F0, H1FV, Histone H1', Histone H1(0), Histone H1.0, Histone H1.0, N-terminally processed |
| Contexte | Histone H1.0 is a ~20 kDa protein. Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers and promote formation of the H3K27me3 mark by the PRC2/EED-EZH2 complex. The histones H1.0 are found in cells that are in terminal stages of differentiation or that have low rates of cell division. 1. Zhou, BR. et al. (2021) Molecular cell 81, 166-182.e6. PMID: 33238161 2. Pehrson, J. et al. (1980) Nature 285, 43-4. PMID: 7374750 |
| Note | For research use only |


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