

| カタログ番号 | HD167012 |
|---|---|
| 説明 |
Recombinant Human HHEX Protein, N-His-KSI (HD167012) expressed in E. coli, spanning Gln2-Gly270. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | Q03014 |
| タンパク質長 | Gln2-Gly270 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 45.65 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | HEX, HHEX, Hematopoietically-expressed homeobox protein HHEX, Homeobox protein HEX, Homeobox protein PRH, PRH, PRHX, Proline-rich homeodomain protein |
| 背景 | Hematopoietically-expressed homeobox protein HHEX is a ~30 kDa protein. Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. Activator of WNT-mediated transcription in conjunction with CTNNB1. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL. Inhibits EIF4E-mediated mRNA nuclear export. 1. Marfil, V. et al. (2010) The Journal of biological chemistry 285, 5726-37. PMID: 20028982 2. Topisirovic, I. et al. (2003) The EMBO journal 22, 689-703. PMID: 12554669 3. Bedford, FK. et al. (1993) Nucleic acids research 21, 1245-9. PMID: 8096636 |
| 注意事項 | For research use only |
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206

中文
English
한국어
日本語
Español
Français
Русский