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| カタログ番号 | HC863012 |
|---|---|
| 説明 |
Recombinant Human HIP1 Protein, N-His (HC863012) expressed in E. coli, spanning Gly23-Ile286. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | O00291 |
| タンパク質長 | Gly23-Ile286 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 32.83 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | HIP-1, HIP-I, HIP1, Huntingtin-interacting protein 1, Huntingtin-interacting protein I |
| 背景 | Huntingtin-interacting protein 1 is a ~116 kDa protein. Plays a role in clathrin-mediated endocytosis and trafficking. Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. Regulates presynaptic nerve terminal activity. Enhances androgen receptor (AR)-mediated transcription. May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway. 1. Waelter, S. et al. (2001) Human molecular genetics 10, 1807-17. PMID: 11532990 2. Mishra, SK. et al. (2001) The Journal of biological chemistry 276, 46230-6. PMID: 11577110 3. Legendre-Guillemin, V. et al. (2002) The Journal of biological chemistry 277, 19897-904. PMID: 11889126 4. Mills, IG. et al. (2005) The Journal of cell biology 170, 191-200. PMID: 16027218 5. Hackam, AS. et al. (2000) The Journal of biological chemistry 275, 41299-308. PMID: 11007801 6. Hyun, TS. et al. (2004) The Journal of biological chemistry 279, 14294-306. PMID: 14732715 7. Wilbur, JD. et al. (2008) The Journal of biological chemistry 283, 32870-9. PMID: 18790740 8. Rao, DS. et al. (2002) The Journal of clinical investigation 110, 351-60. PMID: 12163454 |
| 注意事項 | For research use only |
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