Human HSD17B3 Recombinant Protein (N-His) (HW736022)

Name: Human HSD17B3 Recombinant Protein (N-His)
Brand: abinScience
SKU: HW736022
Price: 211 USD
Availability: InStock

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Numéro de catalogue	HW736022
Description	Recombinant Human HSD17B3 Protein, N-His (HW736022) expressed in E. coli, spanning Ser42-Arg310. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	P37058
Longueur de protéine	Ser42-Arg310
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	32.12 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	17-beta-HSD 3, 17-beta-hydroxysteroid dehydrogenase type 3, EC:1.1.1.62, EC:1.1.1.64, EDH17B3, Estradiol 17-beta-dehydrogenase 2, HSD17B3, SDR12C2, Short chain dehydrogenase/reductase family 12C member 2, Testicular 17-beta-hydroxysteroid dehydrogenase, Testosterone 17-beta-dehydrogenase 3
Contexte	17-beta-hydroxysteroid dehydrogenase type 3 is a ~34 kDa protein. Catalyzes the conversion of 17-oxosteroids to 17beta-hydroxysteroids. Favors the reduction of androstenedione to testosterone. Testosterone is the key androgen driving male development and function. Uses NADPH while the two other EDH17B enzymes use NADH. Androgens such as epiandrosterone, dehydroepiandrosterone, androsterone and androstanedione are accepted as substrates and reduced at C-17. 1. Mindnich, R. et al. (2005) Journal of molecular endocrinology 35, 305-16. PMID: 16216911 2. Engeli, RT. et al. (2016) The Journal of steroid biochemistry and molecular biology 155, 147-54. PMID: 26545797 3. Tsachaki, M. et al. (2017) The Journal of endocrinology 232, 323-335. PMID: 27927697 4. Geissler, WM. et al. (1994) Nature genetics 7, 34-9. PMID: 8075637
Note	For research use only

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Human HSD17B3 Recombinant Protein (N-His).pdf

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