

| Каталожный номер | HW736022 |
|---|---|
| Описание |
Recombinant Human HSD17B3 Protein, N-His (HW736022) expressed in E. coli, spanning Ser42-Arg310. Purity: >90% by SDS-PAGE.
Highlights
|
| Система экспрессии | E. coli |
| Номер доступа | P37058 |
| Длина белка | Ser42-Arg310 |
| Применения | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Виды | Homo sapiens (Human) |
| Характер | Recombinant |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Прогнозируемая молекулярная масса | 32.12 kDa |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | 17-beta-HSD 3, 17-beta-hydroxysteroid dehydrogenase type 3, EC:1.1.1.62, EC:1.1.1.64, EDH17B3, Estradiol 17-beta-dehydrogenase 2, HSD17B3, SDR12C2, Short chain dehydrogenase/reductase family 12C member 2, Testicular 17-beta-hydroxysteroid dehydrogenase, Testosterone 17-beta-dehydrogenase 3 |
| Фон | 17-beta-hydroxysteroid dehydrogenase type 3 is a ~34 kDa protein. Catalyzes the conversion of 17-oxosteroids to 17beta-hydroxysteroids. Favors the reduction of androstenedione to testosterone. Testosterone is the key androgen driving male development and function. Uses NADPH while the two other EDH17B enzymes use NADH. Androgens such as epiandrosterone, dehydroepiandrosterone, androsterone and androstanedione are accepted as substrates and reduced at C-17. 1. Mindnich, R. et al. (2005) Journal of molecular endocrinology 35, 305-16. PMID: 16216911 2. Engeli, RT. et al. (2016) The Journal of steroid biochemistry and molecular biology 155, 147-54. PMID: 26545797 3. Tsachaki, M. et al. (2017) The Journal of endocrinology 232, 323-335. PMID: 27927697 4. Geissler, WM. et al. (1994) Nature genetics 7, 34-9. PMID: 8075637 |
| Примечание | For research use only |
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