

| Número de catálogo | HD306012 |
|---|---|
| Descripción |
Recombinant Human IER5 Protein, N-His-KSI (HD306012) expressed in E. coli, spanning Glu2-Pro166. Purity: >90% by SDS-PAGE.
Highlights
|
| Sistema de expresión | E. coli |
| Número de acceso | Q5VY09 |
| Longitud de proteína | Glu2-Pro166 |
| Aplicaciones | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Especies | Homo sapiens (Human) |
| Naturaleza | Recombinant |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >90% as determined by SDS-PAGE. |
| Peso molecular predicho | 32.95 kDa |
| Forma | Lyophilized |
| Buffer de almacenamiento | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Reconstitución | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Envío | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Nombres alternativos | IER5, Immediate early response gene 5 protein |
| Fondo | Immediate early response gene 5 protein is a ~33 kDa protein. Plays a role as a transcription factor. Mediates positive transcriptional regulation of several chaperone genes during the heat shock response in a HSF1-dependent manner. Mediates negative transcriptional regulation of CDC25B expression. Plays a role in the dephosphorylation of the heat shock factor HSF1 and ribosomal protein S6 kinase (S6K) by the protein phosphatase PP2A. Involved in the regulation of cell proliferation and resistance to thermal stress. 1. Nakamura, S. et al. (2011) PloS one 6, e28011. PMID: 22132193 2. Ishikawa, Y. et al. (2015) The FEBS journal 282, 332-40. PMID: 25355627 3. Ishikawa, Y. et al. (2015) FEBS letters 589, 1150-5. PMID: 25816751 4. Kawabata, S. et al. (2015) FEBS letters 589, 3679-85. PMID: 26496226 |
| Nota | For research use only |
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