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| カタログ番号 | HD306012 |
|---|---|
| 説明 |
Recombinant Human IER5 Protein, N-His-KSI (HD306012) expressed in E. coli, spanning Glu2-Pro166. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | Q5VY09 |
| タンパク質長 | Glu2-Pro166 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 32.95 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | IER5, Immediate early response gene 5 protein |
| 背景 | Immediate early response gene 5 protein is a ~33 kDa protein. Plays a role as a transcription factor. Mediates positive transcriptional regulation of several chaperone genes during the heat shock response in a HSF1-dependent manner. Mediates negative transcriptional regulation of CDC25B expression. Plays a role in the dephosphorylation of the heat shock factor HSF1 and ribosomal protein S6 kinase (S6K) by the protein phosphatase PP2A. Involved in the regulation of cell proliferation and resistance to thermal stress. 1. Nakamura, S. et al. (2011) PloS one 6, e28011. PMID: 22132193 2. Ishikawa, Y. et al. (2015) The FEBS journal 282, 332-40. PMID: 25355627 3. Ishikawa, Y. et al. (2015) FEBS letters 589, 1150-5. PMID: 25816751 4. Kawabata, S. et al. (2015) FEBS letters 589, 3679-85. PMID: 26496226 |
| 注意事項 | For research use only |
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