

| Каталожный номер | HD306012 |
|---|---|
| Описание |
Recombinant Human IER5 Protein, N-His-KSI (HD306012) expressed in E. coli, spanning Glu2-Pro166. Purity: >90% by SDS-PAGE.
Highlights
|
| Система экспрессии | E. coli |
| Номер доступа | Q5VY09 |
| Длина белка | Glu2-Pro166 |
| Применения | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Виды | Homo sapiens (Human) |
| Характер | Recombinant |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Прогнозируемая молекулярная масса | 32.95 kDa |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | IER5, Immediate early response gene 5 protein |
| Фон | Immediate early response gene 5 protein is a ~33 kDa protein. Plays a role as a transcription factor. Mediates positive transcriptional regulation of several chaperone genes during the heat shock response in a HSF1-dependent manner. Mediates negative transcriptional regulation of CDC25B expression. Plays a role in the dephosphorylation of the heat shock factor HSF1 and ribosomal protein S6 kinase (S6K) by the protein phosphatase PP2A. Involved in the regulation of cell proliferation and resistance to thermal stress. 1. Nakamura, S. et al. (2011) PloS one 6, e28011. PMID: 22132193 2. Ishikawa, Y. et al. (2015) The FEBS journal 282, 332-40. PMID: 25355627 3. Ishikawa, Y. et al. (2015) FEBS letters 589, 1150-5. PMID: 25816751 4. Kawabata, S. et al. (2015) FEBS letters 589, 3679-85. PMID: 26496226 |
| Примечание | For research use only |
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