

| Каталожный номер | HD731012 |
|---|---|
| Описание |
Recombinant Human IKZF2 Protein, N-His (HD731012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Система экспрессии | E. coli |
| Номер доступа | Q9UKS7 |
| Длина белка | Asp92-Met227 |
| Применения | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Виды | Homo sapiens (Human) |
| Характер | Recombinant |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | HELIOS, IKZF2, Ikaros family zinc finger protein 2, ZNFN1A2, Zinc finger protein Helios |
| Фон | Zinc finger protein Helios is a ~59 kDa protein. Transcription factor, which stabilizes the noninflammatory phenotype of regulatory T cells (Tregs). May possibly act via STAT5-mediated signaling. Binds IL2 promoter and represses its transcription, possibly by epigenetic silencing, inducing deacetylation of core histones in the IL2 promoter. In Tregs, required for FOXP3 recruitment to the IL2 promoter. Required for outer hair cells maturation and, consequently, for hearing. 1. Mohajeri, A. et al. (2023) Journal of medical genetics 60, 1092-1104. PMID: 37316189 |
| Примечание | For research use only |
Свяжитесь с нами для индивидуальных предложений, оптовых запросов и других вопросов.
Почта: [email protected]
+86-027-65523339
Building C, No. 666, Shen Dun Si Lu, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский