

| Numéro de catalogue | HD420012 |
|---|---|
| Description |
Recombinant Human ING5 Protein, N-His-KSI (HD420012) expressed in E. coli, spanning Ala2-Ala105. Purity: >90% by SDS-PAGE.
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | Q8WYH8 |
| Longueur de protéine | Ala2-Ala105 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Masse moléculaire prédite | 29.33 kDa |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | ING5, Inhibitor of growth protein 5, p28ING5 |
| Contexte | Inhibitor of growth protein 5 is a ~27 kDa protein. Component of the HBO1 complex, which specifically mediates acetylation of histone H3 at 'Lys-14' (H3K14ac) and, to a lower extent, acetylation of histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Through chromatin acetylation it may regulate DNA replication and may function as a transcriptional coactivator. Inhibits cell growth, induces a delay in S-phase progression and enhances Fas-induced apoptosis in an INCA1-dependent manner. 1. Lalonde, ME. et al. (2013) Genes & development 27, 2009-24. PMID: 24065767 2. Doyon, Y. et al. (2006) Molecular cell 21, 51-64. PMID: 16387653 3. Shiseki, M. et al. (2003) Cancer research 63, 2373-8. PMID: 12750254 4. Zhang, F. et al. (2011) PloS one 6, e21505. PMID: 21750715 |
| Note | For research use only |
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