Human IPO5 Recombinant Protein (N-His) (HC865012)

Name: Human IPO5 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC865012
Price: 211 USD
Availability: InStock

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Numéro de catalogue	HC865012
Description	Recombinant Human IPO5 Protein, N-His (HC865012) expressed in E. coli, spanning Met1-Asp333. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	O00410
Longueur de protéine	Met1-Asp333
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	39.55 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	IPO5, Imp5, Importin subunit beta-3, Importin-5, KPNB3, Karyopherin beta-3, RANBP5, Ran-binding protein 5, RanBP5
Contexte	Importin-5 is a ~123 kDa protein. Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. 1. Dean, KA. et al. (2001) Journal of cell science 114, 3479-85. PMID: 11682607 2. Jäkel, S. et al. (1998) The EMBO journal 17, 4491-502. PMID: 9687515
Note	For research use only

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Human IPO5 Recombinant Protein (N-His).pdf

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