

| Numéro de catalogue | HD001012 |
|---|---|
| Description |
Recombinant Human IRF2 Protein, N-His (HD001012) expressed in E. coli, spanning Met1-Pro113. Purity: >90% by SDS-PAGE.
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | P14316 |
| Longueur de protéine | Met1-Pro113 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Masse moléculaire prédite | 15.58 kDa |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | IRF-2, IRF2, Interferon regulatory factor 2 |
| Contexte | Interferon regulatory factor 2 is a ~39 kDa protein. DNA-binding transcription factor that specifically binds to the upstream regulatory region of type I interferon (IFN) and IFN-inducible genes and regulates their expression. Mainly acts as a transcription repressor, repressing expression. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. 1. Danac, JMC. et al. (2024) Molecular cell 84, 2870-2881.e5. PMID: 39013473 2. Tanaka, N. et al. (1993) Molecular and cellular biology 13, 4531-8. PMID: 7687740 3. Oshima, S. et al. (2004) Molecular and cellular biology 24, 6298-310. PMID: 15226432 4. Aziz, F. et al. (1998) Molecular biology reports 25, 1-12. PMID: 9540062 |
| Note | For research use only |
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