Human IRF7 Recombinant Protein (N-His) (HD620012)

Name: Human IRF7 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD620012
Price: 211 USD
Availability: InStock

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50ug
100ug
1mg

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Каталожный номер	HD620012
Описание	Recombinant Human IRF7 Protein, N-His (HD620012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	Q92985
Длина белка	Leu289-Ala503
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	IRF-7, IRF7, Interferon regulatory factor 7
Фон	Interferon regulatory factor 7 is a ~54 kDa protein. Key transcriptional regulator of type I interferon (IFN)-dependent immune responses and plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Can efficiently activate both the IFN-beta (IFNB) and the IFN-alpha (IFNA) genes and mediate their induction via both the virus-activated, MyD88-independent pathway and the TLR-activated, MyD88-dependent pathway. Induces transcription of ubiquitin hydrolase USP25 mRNA in response to lipopolysaccharide (LPS) or viral infection in a type I IFN-dependent manner. Required during both the early and late phases of the IFN gene induction but is more critical for the late than for the early phase. 1. Hwang, SW. et al. (2017) Biochemical and biophysical research communications 486, 700-705. PMID: 28342865 2. Kitagawa, Y. et al. (2017) Journal of virology 91. PMID: 28768858 3. Panne, D. et al. (2007) Cell 129, 1111-23. PMID: 17574024 4. Zhang, Q. et al. (2020) Science (New York, N.Y.) 370. PMID: 32972995 5. Marié, I. et al. (2000) Molecular and cellular biology 20, 8803-14. PMID: 11073981 6. Caillaud, A. et al. (2002) The Journal of biological chemistry 277, 49417-21. PMID: 12374802 7. Kawai, T. et al. (2004) Nature immunology 5, 1061-8. PMID: 15361868 8. Sgarbanti, M. et al. (2007) Annals of the New York Academy of Sciences 1095, 325-33. PMID: 17404045
Примечание	For research use only

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Human IRF7 Recombinant Protein (N-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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g/mol

Formula

C₁ × V₁ = C₂ × V₂

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C₁ (Stock Conc.)

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Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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