

| Каталожный номер | HD995012 |
|---|---|
| Описание |
Recombinant Human ISG20 Protein, N-His (HD995012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Система экспрессии | E. coli |
| Номер доступа | Q96AZ6 |
| Длина белка | Met1-Asp181 |
| Применения | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Виды | Homo sapiens (Human) |
| Характер | Recombinant |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | EC:3.1.13.1, Estrogen-regulated transcript 45 protein, HEM45, ISG20, Interferon-stimulated gene 20 kDa protein, Promyelocytic leukemia nuclear body-associated protein ISG20 |
| Фон | Interferon-stimulated gene 20 kDa protein is a ~20 kDa protein. Interferon-induced antiviral exoribonuclease that acts mainly on single-stranded RNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV). Inhibition of several viruses such as chikungunya virus (CHIKV) does not involve the degradation of viral RNAs, but rather the inhibition of translation of viral proteins. Exerts a translational control over a large panel of non-self RNA substrates while sparing endogenous transcripts. This activity correlates with the protein's ability to localize in cytoplasmic processing bodies. 1. Nguyen, LH. et al. (2001) Biochemistry 40, 7174-9. PMID: 11401564 2. Espert, L. et al. (2003) The Journal of biological chemistry 278, 16151-8. PMID: 12594219 3. Espert, L. et al. (2005) The Journal of general virology 86, 2221-2229. PMID: 16033969 4. Espert, L. et al. (2006) Journal of cellular biochemistry 98, 1320-33. PMID: 16514659 5. Zhou, Z. et al. (2011) Virology 409, 175-88. PMID: 21036379 6. Wu, N. et al. (2019) PLoS pathogens 15, e1008093. PMID: 31600344 |
| Примечание | For research use only |
Свяжитесь с нами для индивидуальных предложений, оптовых запросов и других вопросов.
Почта: [email protected]
+86-027-65523339
Building C, No. 666, Shen Dun Si Lu, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский