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| カタログ番号 | HP896022 |
|---|---|
| 説明 |
Recombinant Human KCNE4 Protein, N-GST & C-His (HP896022) expressed in E. coli, spanning His2-Glu86. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | Q8WWG9 |
| タンパク質長 | His2-Glu86 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 36.84 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | KCNE4, MiRP3, MinK-related peptide 3, Minimum potassium ion channel-related peptide 3, Potassium channel subunit beta MiRP3, Potassium voltage-gated channel subfamily E member 4 |
| 背景 | Potassium voltage-gated channel subfamily E member 4 is a ~23 kDa protein. Ancillary protein that functions as a regulatory subunit of the voltage-gated potassium (Kv) channel complex composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits. KCNE4 beta subunit modulates the gating kinetics and enhances stability of the channel complex. Associates with KCNQ1/KVLTQ1 alpha subunit to inhibit potassium currents. 1. Grunnet, M. et al. (2002) The Journal of physiology 542, 119-30. PMID: 12096056 2. Vanoye, CG. et al. (2009) The Journal of general physiology 134, 207-17. PMID: 19687231 3. Roura-Ferrer, M. et al. (2010) Journal of cellular physiology 225, 692-700. PMID: 20533308 4. Abbott, GW. (2016) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 30, 2959-69. PMID: 27162025 |
| 注意事項 | For research use only |
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