

| Numéro de catalogue | HA290012 |
|---|---|
| Description |
Recombinant Human KCNIP4 Protein, N-His (HA290012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | Q6PIL6 |
| Longueur de protéine | Ser56-Ile250 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | A-type potassium channel modulatory protein 4, CALP, Calsenilin-like protein, KCHIP4, KCNIP4, KChIP4, Kv channel-interacting protein 4, Potassium channel-interacting protein 4 |
| Contexte | Kv channel-interacting protein 4 is a ~28 kDa protein. Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates KCND2 channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. Modulates KCND3/Kv4.3 currents. Isoform 4 does not increase KCND2 expression at the cell membrane. Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane. 1. Morohashi, Y. et al. (2002) The Journal of biological chemistry 277, 14965-75. PMID: 11847232 2. Jerng, HH. et al. (2008) The Journal of biological chemistry 283, 36046-59. PMID: 18957440 3. Tang, YQ. et al. (2013) The Journal of biological chemistry 288, 14727-41. PMID: 23576435 |
| Note | For research use only |
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