Human KCNJ2/Kir2.1 Recombinant Protein (N-His) (HX945012)

Name: Human KCNJ2/Kir2.1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HX945012
Price: 211 USD
Availability: InStock

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Numéro de catalogue	HX945012
Description	Recombinant Human KCNJ2/Kir2.1 Protein, N-His (HX945012) expressed in E. coli, spanning Lys185-Glu349. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	P63252
Longueur de protéine	Lys185-Glu349
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	21.48 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	Cardiac inward rectifier potassium channel, IRK-1, IRK1, Inward rectifier K(+) channel Kir2.1, Inward rectifier potassium channel 2, KCNJ2, Potassium channel, inwardly rectifying subfamily J member 2, hIRK1
Contexte	Inward rectifier potassium channel 2 is a ~48 kDa protein. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium or cesium. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. 1. Fernandes, CAH. et al. (2022) Science advances 8, eabq8489. PMID: 36149965 2. Wood, LS. et al. (1995) Gene 163, 313-7. PMID: 7590287 3. Tare, M. et al. (1998) The Journal of physiology 506 ( Pt 2), 303-18. PMID: 9490857 4. Raab-Graham, KF. et al. (1994) Neuroreport 5, 2501-5. PMID: 7696590
Note	For research use only

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Human KCNJ2/Kir2.1 Recombinant Protein (N-His).pdf

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