Human KCNJ2/Kir2.1 Recombinant Protein (N-His) (HX945012)

Name: Human KCNJ2/Kir2.1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HX945012
Price: 211 USD
Availability: InStock

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1mg

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Каталожный номер	HX945012
Описание	Recombinant Human KCNJ2/Kir2.1 Protein, N-His (HX945012) expressed in E. coli, spanning Lys185-Glu349. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	P63252
Длина белка	Lys185-Glu349
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	21.48 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	Cardiac inward rectifier potassium channel, IRK-1, IRK1, Inward rectifier K(+) channel Kir2.1, Inward rectifier potassium channel 2, KCNJ2, Potassium channel, inwardly rectifying subfamily J member 2, hIRK1
Фон	Inward rectifier potassium channel 2 is a ~48 kDa protein. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium or cesium. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. 1. Fernandes, CAH. et al. (2022) Science advances 8, eabq8489. PMID: 36149965 2. Wood, LS. et al. (1995) Gene 163, 313-7. PMID: 7590287 3. Tare, M. et al. (1998) The Journal of physiology 506 ( Pt 2), 303-18. PMID: 9490857 4. Raab-Graham, KF. et al. (1994) Neuroreport 5, 2501-5. PMID: 7696590
Примечание	For research use only

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Human KCNJ2/Kir2.1 Recombinant Protein (N-His).pdf

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Formula

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

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