Human KCNMA1 Recombinant Protein (N-His) (HD176012)

Name: Human KCNMA1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD176012
Price: 211 USD
Availability: InStock

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Número de catálogo	HD176012
Descripción	Recombinant Human KCNMA1 Protein, N-His (HD176012) expressed in E. coli, spanning Lys408-Arg716. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	Q12791
Longitud de proteína	Lys408-Arg716
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	37.82 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	BK channel, BKCA alpha, Calcium-activated potassium channel subunit alpha-1, Calcium-activated potassium channel, subfamily M subunit alpha-1, K(VCA)alpha, KCNMA, KCNMA1, KCa1.1, Maxi K channel, MaxiK, SLO, Slo homolog, Slo-alpha, Slo1, Slowpoke homolog, hSlo
Fondo	Calcium-activated potassium channel subunit alpha-1 is a ~137 kDa protein. Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity. 1. Tang, XD. et al. (2003) Nature 425, 531-5. PMID: 14523450 2. Li, X. et al. (2018) European journal of human genetics : EJHG 26, 220-229. PMID: 29330545 3. Liang, L. et al. (2019) Human molecular genetics 28, 2937-2951. PMID: 31152168 4. Niu, L. et al. (2020) Proceedings of the National Academy of Sciences of the United States of America 117, 25128-25137. PMID: 32958651
Nota	For research use only

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Datasheet

Human KCNMA1 Recombinant Protein (N-His).pdf

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