Human KCNQ4/Kv7.4 Recombinant Protein (N-His-KSI) (HX132012)

Name: Human KCNQ4/Kv7.4 Recombinant Protein (N-His-KSI)
Brand: abinScience
SKU: HX132012
Price: 211 USD
Availability: InStock

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Número de catálogo	HX132012
Descripción	Recombinant Human KCNQ4/Kv7.4 Protein, N-His-KSI (HX132012) expressed in E. coli, spanning Leu318-Asp695. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	P56696
Longitud de proteína	Leu318-Asp695
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	58.17 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	KCNQ4, KQT-like 4, Potassium channel subunit alpha KvLQT4, Potassium voltage-gated channel subfamily KQT member 4, Voltage-gated potassium channel subunit Kv7.4
Fondo	Potassium voltage-gated channel subfamily KQT member 4 is a ~77 kDa protein. Pore-forming subunit of the voltage-gated potassium (Kv) channel involved in the regulation of sensory cells excitability in the cochlea. KCNQ4/Kv7.4 channel is composed of 4 pore-forming subunits assembled as tetramers. Promotes the outflow of potassium ions in the repolarization phase of action potential which plays a role in regulating membrane potential of excitable cells. The channel conducts a slowly activating and deactivating current. Current often shows some inward rectification at positive potentials. 1. Kubisch, C. et al. (1999) Cell 96, 437-46. PMID: 10025409 2. Zheng, Y. et al. (2022) Neuron 110, 237-247.e4. PMID: 34767770 3. Søgaard, R. et al. (2001) American journal of physiology. Cell physiology 280, C859-66. PMID: 11245603
Nota	For research use only

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Datasheet

Human KCNQ4/Kv7.4 Recombinant Protein (N-His-KSI).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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