Human KDM2A Recombinant Protein (N-His) (HP303012)

Name: Human KDM2A Recombinant Protein (N-His)
Brand: abinScience
SKU: HP303012
Price: 211 USD
Availability: InStock

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Número de catálogo	HP303012
Descripción	Recombinant Human KDM2A Protein, N-His (HP303012) expressed in E. coli, spanning Thr931-Ser1162. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	Q9Y2K7
Longitud de proteína	Thr931-Ser1162
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	28.16 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	CXXC-type zinc finger protein 8, CXXC8, EC:1.14.11.27, F-box and leucine-rich repeat protein 11, F-box protein FBL7, F-box protein Lilina, F-box/LRR-repeat protein 11, FBL11, FBL7, FBXL11, JHDM1A, JmjC domain-containing histone demethylation protein 1A, KDM2A, KIAA1004, Lysine-specific demethylase 2A, [Histone-H3]-lysine-36 demethylase 1A
Fondo	Lysine-specific demethylase 2A is a ~132 kDa protein. Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. 1. Reischl, S. et al. (2015) Journal of biological rhythms 30, 291-301. PMID: 26037310
Nota	For research use only

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Referencias

Datasheet

Human KDM2A Recombinant Protein (N-His).pdf

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