

| Número de catálogo | HD854012 |
|---|---|
| Descripción |
Recombinant Human KIF1A Protein, N-His (HD854012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Sistema de expresión | E. coli |
| Número de acceso | Q12756 |
| Longitud de proteína | Met1-Glu362 |
| Aplicaciones | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Especies | Homo sapiens (Human) |
| Naturaleza | Recombinant |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >90% as determined by SDS-PAGE. |
| Forma | Lyophilized |
| Buffer de almacenamiento | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Reconstitución | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Envío | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Nombres alternativos | ATSV, Axonal transporter of synaptic vesicles, C2orf20, EC:5.6.1.3, KIF1A, Kinesin-like protein KIF1A, Microtubule-based motor KIF1A, Unc-104- and KIF1A-related protein, hUnc-104 |
| Fondo | Kinesin-like protein KIF1A is a ~191 kDa protein. Kinesin motor with a plus-end-directed microtubule motor activity. It is required for anterograde axonal transport of synaptic vesicle precursors. Also required for neuronal dense core vesicles (DCVs) transport to the dendritic spines and axons. The interaction calcium-dependent with CALM1 increases vesicle motility and interaction with the scaffolding proteins PPFIA2 and TANC2 recruits DCVs to synaptic sites. 1. Boyle, L. et al. (2021) HGG advances 2. PMID: 33880452 |
| Nota | For research use only |
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