

| カタログ番号 | HC874012 |
|---|---|
| 説明 |
Recombinant Human KLF11 Protein, N-His (HC874012) expressed in E. coli, spanning Gly400-Ala512. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | O14901 |
| タンパク質長 | Gly400-Ala512 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 15.20 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | FKLF, KLF11, Krueppel-like factor 11, TGFB-inducible early growth response protein 2, TIEG-2, TIEG2, Transforming growth factor-beta-inducible early growth response protein 2 |
| 背景 | Krueppel-like factor 11 is a ~55 kDa protein. Transcription factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth. Represses transcription of SMAD7 which enhances TGF-beta signaling. Induces apoptosis. 1. Asano, H. et al. (1999) Molecular and cellular biology 19, 3571-9. PMID: 10207080 2. Cook, T. et al. (1998) The Journal of biological chemistry 273, 25929-36. PMID: 9748269 3. Blau, CA. et al. (2005) The Journal of biological chemistry 280, 36642-7. PMID: 16131492 |
| 注意事項 | For research use only |
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