Human LPIN1 Recombinant Protein (N-His) (HD221012)

Name: Human LPIN1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD221012
Price: 211 USD
Availability: InStock

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Numéro de catalogue	HD221012
Description	Recombinant Human LPIN1 Protein, N-His (HD221012) expressed in E. coli, spanning Asn621-Pro851. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	Q14693
Longueur de protéine	Asn621-Pro851
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	28.53 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	EC:3.1.3.4, KIAA0188, LPIN1, Lipin-1, Phosphatidate phosphatase LPIN1
Contexte	Phosphatidate phosphatase LPIN1 is a ~98 kDa protein. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis and therefore controls the metabolism of fatty acids at different levels. Is involved in adipocyte differentiation. Recruited at the mitochondrion outer membrane and is involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol. Acts also as nuclear transcriptional coactivator for PPARGC1A/PPARA regulatory pathway to modulate lipid metabolism gene expression. 1. Han, GS. et al. (2010) The Journal of biological chemistry 285, 14628-38. PMID: 20231281 2. Eaton, JM. et al. (2013) The Journal of biological chemistry 288, 9933-9945. PMID: 23426360 3. Li, TY. et al. (2018) Nature communications 9, 1916. PMID: 29765047 4. MacVicar, T. et al. (2019) Nature 575, 361-365. PMID: 31695197
Note	For research use only

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Human LPIN1 Recombinant Protein (N-His).pdf

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