Human LUZP1 Recombinant Protein (N-His) (HC252012)

Name: Human LUZP1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC252012
Price: 211 USD
Availability: InStock

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Número de catálogo	HC252012
Descripción	Recombinant Human LUZP1 Protein, N-His (HC252012) expressed in E. coli, spanning Met157-Gln350. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	Q86V48
Longitud de proteína	Met157-Gln350
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	25.22 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	Filamin mechanobinding actin cross-linking protein, Fimbacin, LUZP1, Leucine zipper protein 1
Fondo	Leucine zipper protein 1 is a ~120 kDa protein. F-actin cross-linking protein. Stabilizes actin and acts as a negative regulator of primary cilium formation. Positively regulates the phosphorylation of both myosin II and protein phosphatase 1 regulatory subunit PPP1R12A/MYPT1 and promotes the assembly of myosin II stacks within actin stress fibers. Inhibits the phosphorylation of myosin light chain MYL9 by DAPK3 and suppresses the constriction velocity of the contractile ring during cytokinesis. Binds to microtubules and promotes epithelial cell apical constriction by up-regulating levels of diphosphorylated myosin light chain (MLC) through microtubule-dependent inhibition of MLC dephosphorylation by myosin phosphatase. 1. Wang, J. et al. (2019) Biochemistry 58, 4737-4743. PMID: 30990684 2. Gonçalves, J. et al. (2020) The Journal of cell biology 219. PMID: 32496561 3. Wang, L. et al. (2024) Cellular and molecular life sciences : CMLS 81, 248. PMID: 38832964 4. Hyodo, T. et al. (2024) The FEBS journal 291, 927-944. PMID: 38009294
Nota	For research use only

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Referencias

Datasheet

Human LUZP1 Recombinant Protein (N-His).pdf

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Formula

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