Human LYNX1 Recombinant Protein (N-His) (HC988012)

Name: Human LYNX1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC988012
Price: 211 USD
Availability: InStock

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Número de catálogo	HC988012
Descripción	Recombinant Human LYNX1 Protein, N-His (HC988012) expressed in E. coli, spanning Leu21-Leu116. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	P0DP58
Longitud de proteína	Leu21-Leu116
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	12.85 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	Endogenous prototoxin LYNX1, LYNX1, Ly-6/neurotoxin-like protein 1, Testicular tissue protein Li 112
Fondo	Ly-6/neurotoxin-like protein 1 is a ~12 kDa protein. Acts in different tissues through interaction to nicotinic acetylcholine receptors (nAChRs). The proposed role as modulator of nAChR activity seems to be dependent on the nAChR subtype and stoichiometry, and to involve an effect on nAChR trafficking and its cell surface expression, and on single channel properties of the nAChR inserted in the plasma membrane. Modulates functional properties of nicotinic acetylcholine receptors (nAChRs) to prevent excessive excitation, and hence neurodegeneration. Enhances desensitization by increasing both the rate and extent of desensitization of alpha-4:beta-2-containing nAChRs and slowing recovery from desensitization. Promotes large amplitude ACh-evoked currents through alpha-4:beta-2 nAChRs. 1. Lyukmanova, EN. et al. (2011) The Journal of biological chemistry 286, 10618-27. PMID: 21252236 2. George, AA. et al. (2017) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 31, 1398-1420. PMID: 28100642
Nota	For research use only

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Datasheet

Human LYNX1 Recombinant Protein (N-His).pdf

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