Human LYNX1 Recombinant Protein (N-His) (HC988012)

Name: Human LYNX1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC988012
Price: 211 USD
Availability: InStock

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Numéro de catalogue	HC988012
Description	Recombinant Human LYNX1 Protein, N-His (HC988012) expressed in E. coli, spanning Leu21-Leu116. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	P0DP58
Longueur de protéine	Leu21-Leu116
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	12.85 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	Endogenous prototoxin LYNX1, LYNX1, Ly-6/neurotoxin-like protein 1, Testicular tissue protein Li 112
Contexte	Ly-6/neurotoxin-like protein 1 is a ~12 kDa protein. Acts in different tissues through interaction to nicotinic acetylcholine receptors (nAChRs). The proposed role as modulator of nAChR activity seems to be dependent on the nAChR subtype and stoichiometry, and to involve an effect on nAChR trafficking and its cell surface expression, and on single channel properties of the nAChR inserted in the plasma membrane. Modulates functional properties of nicotinic acetylcholine receptors (nAChRs) to prevent excessive excitation, and hence neurodegeneration. Enhances desensitization by increasing both the rate and extent of desensitization of alpha-4:beta-2-containing nAChRs and slowing recovery from desensitization. Promotes large amplitude ACh-evoked currents through alpha-4:beta-2 nAChRs. 1. Lyukmanova, EN. et al. (2011) The Journal of biological chemistry 286, 10618-27. PMID: 21252236 2. George, AA. et al. (2017) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 31, 1398-1420. PMID: 28100642
Note	For research use only

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Human LYNX1 Recombinant Protein (N-His).pdf

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